Thursdays. Route 66 Casino Hotel is a full-service casino, restaurant and hotel property located 17 miles west of downtown Albuquerque on Interstate 40 at Exit route 66 casino hours. Saturdays. Poker alley and bingo parlor. Located less than 20 minutes from Downtown Albuquerque, you won't have to worry about traffic lights or. Open 24 hours, 7 days a week! What's happening this April. The Route 66 Casino Hotel offers over 1, slot and video poker machines, 26 table games, a seat bingo hall, a dedicated poker room with 10 tables, five. Open daily from 7 AM - 2 AM! Under the initial reopening, you can Get Your Kicks on our slot machines and sports betting at The Book. Get your kicks at route 66! Stay and Go Play! Route 66 Casino Hotel. Daily Hours of Operation: 7 AM – 2 AM Details on open amenities and frequently asked questions can be. More than 1, slots, craps, roulette and blackjack. Sundays. . Enjoy our indoor pool that features an outdoor sundeck. The Route 66 Casino Hotel is now open. International buffet, travel center, nightclub, 3-star hotel. Located less than 20 minutes from Downtown Albuquerque, you won't have to worry about traffic lights or commuters, the drive is straight and stress free highway.